Pharmaceutical Research - Volume 19 Number 7, Jul 2002 Articles

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Pharmaceutical Research
Volume 19 Number 7, Jul 2002

Pharmaceutical Research

Volume 19 Number 7, Jul 2002

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Evaluation of the AERx Pulmonary Delivery System for Systemic Delivery of a Poorly Soluble Selective D-1 Agonist, ABT-431
Author(s): Franklin W. Okumu; Rai-Yun Lee; James D. Blanchard; Anthony Queirolo; Christine M. Woods; Peter M. Lloyd; Jerry Okikawa; Igor Gonda; Stephen J. Farr; Reid Rubsamen; Akwete L. Adjei; Richard J. Bertz
Characterization of Mefenamic Acid-Guaiacol Ester: Stability and Transport Across Caco-2 Cell Monolayers
Author(s): Vimon Tantishaiyakul; Kamonthip Wiwattanawongsa; Sirirat Pinsuwan; Srirat Kasiwong; Narubodee Phadoongsombut; Sanae Kaewnopparat; Nattha Kaewnopparat; Yon Rojanasakul
Modifying the Bitterness of Selected Oral Pharmaceuticals with Cation and Anion Series of Salts
Author(s): Russell S. J. Keast; Paul A. S. Breslin
Influence of Structural Variations in Peptidomimetic 4-Amidinophenylalanine-Derived Thrombin Inhibitors on Plasma Clearance and Biliary Excretion in Rats
Author(s): Jörg Hauptmann; Torsten Steinmetzer; Helmut Vieweg; Peter Wikström; Jörg Stürzebecher
The N-Demethylation of the Doxepin Isomers Is Mainly Catalyzed by the Polymorphic CYP2C19
Author(s): Sebastian Härtter; Gunnel Tybring; Thomas Friedberg; Harald Weigmann; Christoph Hiemke
Differential Modulation of P-Glycoprotein Expression and Activity by Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors in Cell Culture
Author(s): Elke Störmer; Lisa L. von Moltke; Michael D. Perloff; David J. Greenblatt
A Novel in Vitro Delivery System for Assessing the Biological Integrity of Protein upon Release from PLGA Microspheres
Author(s): Anne Aubert-Pouëssel; David C. Bibby; Marie-Claire Venier-Julienne; François Hindré; Jean-Pierre Benoît
Sustained Release Chemotherapeutic Microspheres Provide Superior Efficacy over Systemic Therapy and Local Bolus Infusions
Author(s): Dwaine F. Emerich; Pamela Snodgrass; Denise Lafreniere; Reginald L. Dean; Heather Salzberg; Joanne Marsh; Brigido Perdomo; Mahin Arastu; Shelley R. Winn; Raymond T. Bartus
Long-Circulating Poly(Ethylene Glycol)-Modified Gelatin Nanoparticles for Intracellular Delivery
Author(s): Goldie Kaul; Mansoor Amiji
Relationship Between Particle Size and Impurity Incorporation During Crystallization of (+)-Pseudoephedrine Hydrochloride, Acetaminophen, and Adipic Acid from Aqueous Solution
Author(s): Chong-Hui Gu; David J. W. Grant
AAPS Update
Book Reviews
Biopharmaceutics Classification System: The Scientific Basis for Biowaiver Extensions
Author(s): Lawrence X. Yu; Gordon L. Amidon; James E. Polli; Hong Zhao; Mehul U. Mehta; Dale P. Conner; Vinod P. Shah; Lawrence J. Lesko; Mei-Ling Chen; Vincent H. L. Lee; Ajaz S. Hussain
Rational Design of Peptide-Based Tumor Vaccines
Author(s): Wilson S. Meng; Lisa H. Butterfield
Cationic Cholesterol Promotes Gene Transfection Using the Nuclear Localization Signal in Protamine
Author(s): Ari Noguchi; Naohide Hirashima; Mamoru Nakanishi
Genetic Immunization Using Nanoparticles Engineered from Microemulsion Precursors
Author(s): Zhengrong Cui; Russell J. Mumper
Bilayer Films for Mucosal (Genetic) Immunization via the Buccal Route in Rabbits
Author(s): Zhengrong Cui; Russell J. Mumper
Controlled Release of Plasmid DNA from a Genetically Engineered Silk-Elastinlike Hydrogel
Author(s): Zaki Megeed; Joseph Cappello; Hamidreza Ghandehari
The Lower-Generation Polypropylenimine Dendrimers Are Effective Gene-Transfer Agents
Author(s): Bernd H. Zinselmeyer; Simon P. Mackay; Andreas G. Schatzlein; Ijeoma F. Uchegbu
Glucose-Modulated Transgene Expression via Recombinant Adeno-Associated Virus
Author(s): Ya-Wun Yang; Yuan-Chiao Hsieh; Chih-Kai Chao
Prediction of Drug Transport Through the Blood-Brain Barrier in Vivo: A Comparison Between Two in Vitro Cell Models
Author(s): Stefan Lundquist; Mila Renftel; Julien Brillault; Laurence Fenart; Roméo Cecchelli; Marie-Pierre Dehouck
Role of Ascorbic Acid in Stratum Corneum Lipid Models Exposed to UV Irradiation
Author(s): Hagen Trommer; Rolf Böttcher; Andreas Pöppl; Joachim Hoentsch; Siegfried Wartewig; Reinhard H. H. Neubert
Transdermal Delivery of Pergolide from Surfactant-Based Elastic and Rigid Vesicles: Characterization and in Vitro Transport Studies
Author(s): P. Loan Honeywell-Nguyen; Peter M. Frederik; Paul H. H. Bomans; Hans E. Junginger; Joke A. Bouwstra
Nasal Delivery of Insulin Using Novel Chitosan Based Formulations: A Comparative Study in Two Animal Models Between Simple Chitosan Formulations and Chitosan Nanoparticles
Author(s): A. M. Dyer; M. Hinchcliffe; P. Watts; J. Castile; I. Jabbal-Gill; R. Nankervis; A. Smith; L. Illum

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