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Volume 14 Number 1, Mar 2012

Volume 14 Number 1, Mar 2012

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Pharmacodynamic Modeling of Sequence-Dependent Antitumor Activity of Insulin-like Growth Factor Blockade and Gemcitabine
Author(s): Amit Khatri; Richard C. Brundage; Jessica M. Hull; Brent W. Williams; Douglas Yee; Mark N. Kirstein
Absorption Enhancers: Applications and Advances
Author(s): Bruce J. Aungst
Ligand-Binding Assays in the 21st Century Laboratory: Recommendations for an Automated Data Interchange Process
Author(s): Sheldon S. Leung; Joel Usansky; Robert Lynde; Theingi Thway; Robert Hendricks; David Rusnak
Ligand Binding Assays in the 21st Century Laboratory: Platforms
Author(s): Franklin P. Spriggs; Zhandong Don Zhong; Afshin Safavi; Darshana Jani; Narasaiah Dontha; Anita Kant; Jenny Ly; Lia Brilando; Karolina Österlund; Nathalie Rouleau; Saloumeh Kadkhodayan Fischer; Martin Boissonneault; Chad Ray
Covariate Pharmacokinetic Model Building in Oncology and its Potential Clinical Relevance
Author(s): Markus Joerger
Structure-Based Virtual Screening for Drug Discovery: a Problem-Centric Review
Author(s): Tiejun Cheng; Qingliang Li; Zhigang Zhou; Yanli Wang; Stephen H. Bryant

In Themed Issue: New Paradigms in Pharmaceutical Sciences: In Silico Drug Discovery
Ligand Binding Assays in the 21st Century Laboratory: Automation
Author(s): Ago B. Ahene; Chris Morrow; David Rusnak; Susan Spitz; Joel Usansky; Holger Pils; Francesca Civoli; Kinnari Pandya; Brian Sue; Daniel Leach; John Derent
Common Deficiencies with Bioequivalence Submissions in Abbreviated New Drug Applications Assessed by FDA
Author(s): Qing Liu; Barbara M. Davit; Svetlana A. Cherstniakova; Suman Dandamudi; Johnetta F. Walters; Christina H. Lee; Kimberly W. Raines; Ke Ren; Leeh N. Williamson; Dale P. Conner
Comparison of Intestinal Absorption and Disposition of Structurally Similar Bioactive Flavones in Radix Scutellariae
Author(s): Chenrui Li; Li Zhang; Limin Zhou; Siu Kwan Wo; Ge Lin; Zhong Zuo
PEGylation of a Factor VIII–Phosphatidylinositol Complex: Pharmacokinetics and Immunogenicity in Hemophilia A Mice
Author(s): Aaron Peng; Matthew P. Kosloski; Genki Nakamura; Hong Ding; Sathy V. Balu-Iyer
Synthesis and Pharmacological Characterization of a Novel Sigma Receptor Ligand with Improved Metabolic Stability and Antagonistic Effects Against Methamphetamine
Author(s): Michael J. Seminerio; Matthew J. Robson; Ahmed H. Abdelazeem; Christophe Mesangeau; Seshulatha Jamalapuram; Bonnie A. Avery; Christopher R. McCurdy; Rae R. Matsumoto
The Risk of Recurrence in Breast Cancer Patients Treated with Tamoxifen: Polymorphisms of CYP2D6 and ABCB1
Author(s): L. K. Teh; N. I. Mohamed; M. Z. Salleh; M. Rohaizak; N. S. Shahrun; J. J. Saladina; J. K. S. Shia; H. Roslan; S. Sood; T. S. Rajoo; S. P. Muniandy; G. Henry; H. A. Ngow; K. T. Hla U; J. Din
On Average: Data Exploration Based on Means Can Be Misleading
Author(s): Adrian Dunne; Mila Etropolski; An Vermeulen; Partha Nandy
Effect of Cyclosporine and Rifampin on the Pharmacokinetics of Macitentan, a Tissue-Targeting Dual Endothelin Receptor Antagonist
Author(s): Shirin Bruderer; Päivi Äänismaa; Marie-Claude Homery; Stephanie Häusler; Kyle Landskroner; Patricia N. Sidharta; Alexander Treiber; Jasper Dingemanse
Modification of Disodium Cromoglycate Passage Across Lung Epithelium In Vitro Via Incorporation into Polymeric Microparticles
Author(s): Mehra Haghi; Rania Salama; Daniela Traini; Mary Bebawy; Paul M. Young
Alteration in P-glycoprotein Functionality Affects Intrabrain Distribution of Quinidine More Than Brain Entry—A Study in Rats Subjected to Status Epilepticus by Kainate
Author(s): Stina Syvänen; Maarten Schenke; Dirk-Jan Berg; Rob A. Voskuyl; Elizabeth C. Lange
Disposition of Human Recombinant Lubricin in Naive Rats and in a Rat Model of Post-traumatic Arthritis After Intra-articular or Intravenous Administration
Author(s): Yulia Vugmeyster; Qin Wang; Xin Xu; John Harrold; Daren Daugusta; Jian Li; Richard Zollner; Carl R. Flannery; Moisés A. Rivera-Bermúdez

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Volume 14 Number 1, Mar 2012

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