The AAPS Journal - Vol. 8 Number 3, Sep 2006 Articles

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Vol. 8 Number 3, Sep 2006

The AAPS Journal

Vol. 8 Number 3, Sep 2006

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Pharmacokinetics and bioavailability of the isoflavone biochanin A in rats
Author(s): Young Jin Moon; Kazuko Sagawa; Kosea Frederick; Shuzhong Zhang; Marilyn E. Morris
Multiple molecular targets in cancer chemoprevention by curcumin
Author(s): Rajesh L. Thangapazham; Anuj Sharma; Radha K. Maheshwari
New paradigms and tools in drug design for pain and addiction
Author(s): Victor J. Hruby; Frank Porreca; Henry I. Yamamura; Gordon Tollin; Richard S. Agnes; Yeon Sun Lee; Minying Cai; Isabel Alves; Scott Cowell; Eva Varga; Peg Davis; Zdzislaw Salamon; William Roeske; Todd Vanderah; Josephine Lai
Targeted lipidomics: Discovery of new fatty acyl amides
Author(s): Bo Tan; Heather B. Bradshaw; Neta Rimmerman; Harini Srinivasan; Y. William Yu; Jocelyn F. Krey; M. Francesca Monn; Jay Shih-Chieh Chen; Sherry Shu-Jung Hu; Sarah R. Pickens; J. Michael Walker
Issues related to targeted delivery of proteins and peptides
Author(s): Yingjuan Lu; Jun Yang; Emanuela Sega
Agmatine: Biological role and therapeutic potentials in morphine analgesia and dependence
Author(s): Soundar Regunathan
The kinetics of thiol-mediated decomposition of S-nitrosothiols
Author(s): Teh-Min Hu; Ta-Chuan Chou
Rapid in vivo oral screening in rats: Reliability, acceptance criteria, and filtering efficiency
Author(s): Hong Mei; Walter Korfmacher; Richard Morrison
Effects of protein aggregates: An immunologic perspective
Author(s): Amy S. Rosenberg
MicroPET investigation of chronic long-term neurotoxicity from heavy ion irradiation
Author(s): Onarae Rice; Sandra Saintvictor; Michael Michaelides; Panayotis Thanos; Samuel John Gatley
Searching for polymorphisms that affect gene expression and mRNA processing: Example ABCB1 (MDR1)
Author(s): Danxin Wang; Wolfgang Sadée
Mitochondria-targeted peptide antioxidants: Novel neuroprotective agents
Author(s): Hazel H. Szeto
Immunotoxins for targeted cancer therapy
Author(s): Robert J. Kreitman
Development and evaluation of a population pharmacokinetic-pharmacodynamic model of darbepoetin alfa in patients with nonmyeloid malignancies undergoing multicycle chemotherapy
Author(s): Balaji Agoram; Anne C. Heatherington; Marc R. Gastonguay
Is any measurement method optimal for all aggregate sizes and types?
Author(s): John S. Philo
Protein aggregation and bioprocessing
Author(s): Mary E. M. Cromwell; Eric Hilario; Fred Jacobson
A critical review of analytical ultracentrifugation and field flow fractionation methods for measuring protein aggregation
Author(s): Jun Liu; James D. Andya; Steven J. Shire
Role of analytical ultracentrifugation in assessing the aggregation of protein biopharmaceuticals
Author(s): Steven A. Berkowitz
Modulation of microglial pro-inflammatory and neurotoxic activity for the treatment of Parkinson’s disease
Author(s): Bin Liu
Corrigendum: Current status of immunologic approaches to treating tobacco dependence: Vaccines and nicotine-specific antibodies
Author(s): Mark G. LeSage; Daniel E. Keyler; Paul R. Pentel

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