AAPS PharmSciTech - Vol. 12 Number 1, Mar 2011 Articles

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Vol. 12 Number 1, Mar 2011

AAPS PharmSciTech

Vol. 12 Number 1, Mar 2011

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Transdermal Delivery of an Anti-Cancer Drug via W/O Emulsions Based on Alkyl Polyglycosides and Lecithin: Design, Characterization, and In Vivo Evaluation of the Possible Irritation Potential in Rats
Author(s): Aliaa Nabil ElMeshad; Mina Ibrahim Tadros
Recent Advancement of Chitosan-Based Nanoparticles for Oral Controlled Delivery of Insulin and Other Therapeutic Agents
Author(s): Anumita Chaudhury; Surajit Das
Comparison of Spray Freeze Drying and the Solvent Evaporation Method for Preparing Solid Dispersions of Baicalein with Pluronic F68 to Improve Dissolution and Oral Bioavailability
Author(s): Xiuqiong He; Lixia Pei; Henry H. Y. Tong; Ying Zheng
Quality by Design and Process Analytical Technology for Sterile Products—Where Are We Now?
Author(s): Bryan S. Riley; Xuhong Li
Optimization of Process Parameters for a Quasi-Continuous Tablet Coating System Using Design of Experiments
Author(s): Christine Cahyadi; Paul Wan Sia Heng; Lai Wah Chan
Development of Push–Pull Osmotic Tablets Using Chitosan–Poly(Acrylic Acid) Interpolymer Complex as an Osmopolymer
Author(s): Wichan Ketjinda; Nuttanan Sinchaipanid; Pichet Limsuwan; Hans Leuenberger; Ampol Mitrevej
Development and Evaluation of Cetirizine HCl Taste-Masked Oral Disintegrating Tablets
Author(s): Dionysios Dennis Douroumis; Andreas Gryczke; Silke Schminke
Controlled Release of Oral Tetrahydrocurcumin from a Novel Self-Emulsifying Floating Drug Delivery System (SEFDDS)
Author(s): Saipin Setthacheewakul; Wichan Kedjinda; Duangkhae Maneenuan; Ruedeekorn Wiwattanapatapee
In Vitro–In Vivo Correlation for Gliclazide Immediate-Release Tablets Based on Mechanistic Absorption Simulation
Author(s): Sandra Grbic; Jelena Parojcic; Svetlana Ibric; Zorica Djuric
The Biodegradation of Zein In Vitro and In Vivo and its Application in Implants
Author(s): Teng Lin; Chuanhua Lu; Ligen Zhu; Tao Lu
Physicochemical Characterization of NPC 1161C, A Novel Antimalarial 8-Aminoquinoline, in Solution and Solid State
Author(s): Asish Kumar Dutta; Steven P. Stodghill; Christy M. Wyandt
Development and Evaluation of Chitosan-Coated Liposomes for Oral DNA Vaccine: The Improvement of Peyer’s Patch Targeting Using a Polyplex-Loaded Liposomes
Author(s): Sunee Channarong; Wanpen Chaicumpa; Nuttanan Sinchaipanid; Ampol Mitrevej
Pectin Matrix as Oral Drug Delivery Vehicle for Colon Cancer Treatment
Author(s): Tin Wui Wong; Gaia Colombo; Fabio Sonvico
Formulation and In Vitro Evaluation of Xanthan Gum or Carbopol 934-Based Mucoadhesive Patches, Loaded with Nicotine
Author(s): Rana Abu-Huwaij; Rana M. Obaidat; Kamal Sweidan; Yusuf Al-Hiari
Sound Practices for Consistent Human Visual Inspection
Author(s): James A. Melchore
Comparison of Compendial Antimicrobial Effectiveness Tests: A Review
Author(s): Cheryl L. Moser; Brian K. Meyer
A Composite Polyelectrolytic Matrix for Controlled Oral Drug Delivery
Author(s): Priya Bawa; Viness Pillay; Yahya Essop Choonara; Lisa Claire Toit; Valence Methaius Kessy Ndesendo; Pradeep Kumar
Novel Jojoba Oil-Based Emulsion Gel Formulations for Clotrimazole Delivery
Author(s): Mostafa Shahin; Seham Abdel Hady; Mohammed Hammad; Nahed Mortada
Complexities of Particulate Matter Measurement in Parenteral Formulations of Small-Molecule Amphiphilic Drugs
Author(s): Magali B. Hickey; Sara Waggener; Dilip Gole; Ilias Jimidar; Hans Vermeersch; Poe Ratanabanangkoon; Arjen P. Tinke; Örn Almarsson
Purification and Characterization of Novel α-Amylase from Bacillus subtilis KIBGE HAS
Author(s): Saeeda Bano; Shah Ali Ul Qader; Afsheen Aman; Muhammad Noman Syed; Abid Azhar
NIR Spectroscopy Applications in the Development of a Compacted Multiparticulate System for Modified Release
Author(s): Stuart L. Cantor; Stephen W. Hoag; Christopher D. Ellison; Mansoor A. Khan; Robbe C. Lyon
Cyclodextrin-Based Nanosponges for Delivery of Resveratrol: In Vitro Characterisation, Stability, Cytotoxicity and Permeation Study
Author(s): Khalid A. Ansari; Pradeep R. Vavia; Francesco Trotta; Roberta Cavalli
Evaluation of Ionotropic Cross-Linked Chitosan/Gelatin B Microspheres of Tramadol Hydrochloride
Author(s): Sanat Kumar Basu; Kunchu Kavitha; Mani Rupeshkumar
Towards Integrated Drug Substance and Drug Product Design for an Active Pharmaceutical Ingredient Using Particle Engineering
Author(s): Eleftherios Kougoulos; Ian Smales; Hugh M. Verrier
A Novel Injection-Molded Capsular Device for Oral Pulsatile Delivery Based on Swellable/Erodible Polymers
Author(s): Andrea Gazzaniga; Matteo Cerea; Alberto Cozzi; Anastasia Foppoli; Alessandra Maroni; Lucia Zema
The Effects of Excipients and Particle Engineering on the Biophysical Stability and Aerosol Performance of Parathyroid Hormone (1-34) Prepared as a Dry Powder for Inhalation
Author(s): Sunday A. Shoyele; Neeraj Sivadas; Sally-Ann Cryan
Product Lifecycle Approach to Cascade Impaction Measurements
Author(s): Terrence P. Tougas; Dave Christopher; Jolyon Mitchell; Svetlana Lyapustina; Michiel Oort; Richard Bauer; Volker Glaab
Introduction of a Theoretical Splashing Degree to Assess the Performance of Low-Viscosity Oils in Filling of Capsules
Author(s): Andreas Niederquell; Martin Kuentz
Practical Considerations in the Measurement of the Internal Relative Humidity of Pharmaceutical Packages with Data Loggers
Author(s): Eric D. Nelson; Henry Huang
Assessment of the Influence Factors on Nasal Spray Droplet Velocity Using Phase-Doppler Anemometry (PDA)
Author(s): Xiaofei Liu; William H. Doub; Changning Guo
Templated Ultrathin Polyelectrolyte Microreservoir for Delivery of Bovine Serum Albumin: Fabrication and Performance Evaluation
Author(s): Girish K. Gupta; Vikas Jain; Prabhat Ranjan Mishra
Sustained Release of Amoxicillin from Ethyl Cellulose-Coated Amoxicillin/Chitosan–Cyclodextrin-Based Tablets
Author(s): Kultida Songsurang; Jatuporn Pakdeebumrung; Narong Praphairaksit; Nongnuj Muangsin
Prolonged Intragastric Drug Delivery Mediated by Eudragit®E-Carrageenan Polyelectrolyte Matrix Tablets
Author(s): Ahmad Bani-Jaber; Leena Al-Aani; Hatim Alkhatib; Bashar Al-Khalidi
Solution Formulation Development of a VEGF Inhibitor for Intravitreal Injection
Author(s): Michelle T. Marra; Penney Khamphavong; Peter Wisniecki; Hovhannes J. Gukasyan; Katsuhiko Sueda
Emerging Freeze-Drying Process Development and Scale-up Issues
Author(s): Sajal Manubhai Patel; Michael J. Pikal
Optimization of the Secondary Drying Step in Freeze Drying Using TDLAS Technology
Author(s): Stefan C. Schneid; Henning Gieseler; William J. Kessler; Suman A. Luthra; Michael J. Pikal
Cellulose-Based Matrix Microspheres of Prednisolone Inclusion Complex: Preparation and Characterization
Author(s): Mohanraj Palanisamy; Jasmina Khanam
Solid Dispersions of Imidazolidinedione by PEG and PVP Polymers with Potential Antischistosomal Activities
Author(s): Francimary L. Guedes; Boaz G. Oliveira; Marcelo Z. Hernandes; Carlos A. Simone; Francisco J. B. Veiga; Maria do Carmo A. Lima; Ivan R. Pitta; Suely L. Galdino; Pedro José Rolim Neto
Biologics Formulation Factors Affecting Metal Leachables from Stainless Steel
Author(s): Shuxia Zhou; Christian Schöneich; Satish K. Singh
Development of Indinavir Submicron Lipid Emulsions Loaded with Lipoamino Acids—In Vivo Pharmacokinetics and Brain-Specific Delivery
Author(s): Swetha Bollam; Prabhakar Kandadi; Shashank Sridhar Apte; Kishan Veerabrahma
Transdermal Delivery of Proteins
Author(s): Haripriya Kalluri; Ajay K. Banga
A QbD Case Study: Bayesian Prediction of Lyophilization Cycle Parameters
Author(s): Linas Mockus; David LeBlond; Prabir K. Basu; Rakhi B. Shah; Mansoor A. Khan
Erratum: Rheological Evaluation of Inter-Grade and Inter-Batch Variability of Sodium Alginate
Author(s): Shao Fu; Ankur Thacker; Diana M. Sperger; Riccardo L. Boni; Sachin Velankar; Eric J. Munson; Lawrence H. Block
Erratum to: Enhanced Stability of Ramipril in Nanoemulsion Containing Cremophor-EL: A Technical Note
Author(s): Sheikh Shafiq; Faiyaz Shakeel
Erratum to: A Novel Injection-Molded Capsular Device for Oral Pulsatile Delivery Based on Swellable/Erodible Polymers
Author(s): Andrea Gazzaniga; Matteo Cerea; Alberto Cozzi; Anastasia Foppoli; Alessandra Maroni; Lucia Zema
Design and Mechanism of On–Off Pulsed Drug Release Using Nonenteric Polymeric Systems via pH Modulation
Author(s): Phuong Ha-Lien Tran; Jae-Seung Choe; Thao Truong-Dinh Tran; Young Min Park; Beom-Jin Lee
Measuring Surface Roughness of Pharmaceutical Powders Using Vapor Sorption Methods
Author(s): Daniel J. Burnett; Jerry Y. Y. Heng; Frank Thielmann; Armando R. Garcia; Majid Naderi; Manaswini Acharya
Recent Advances in Lipid Nanoparticle Formulations with Solid Matrix for Oral Drug Delivery
Author(s): Surajit Das; Anumita Chaudhury
Guar Gum, Xanthan Gum, and HPMC Can Define Release Mechanisms and Sustain Release of Propranolol Hydrochloride
Author(s): Muhammad Akhlaq Mughal; Zafar Iqbal; Steven Henry Neau
The Manufacture of Low-Dose Oral Solid Dosage Form to Support Early Clinical Studies Using an Automated Micro-Filing System
Author(s): Mingda Bi; Changquan Calvin Sun; Francisco Alvarez; Fernando Alvarez-Nunez
Stability Models for Sequential Storage
Author(s): Emil M. Friedman; Sam C. Shum

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