AAPS PharmSciTech - Volume 14 Number 1, Mar 2013 Articles

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AAPS PharmSciTech

Volume 14 Number 1, Mar 2013

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Effect of Polysorbate 80 Concentration on Thermal and Photostability of a Monoclonal Antibody
Author(s): Meera Agarkhed; Courtney O’Dell; Ming-Ching Hsieh; Jingming Zhang; Joel Goldstein; Arvind Srivastava
Molecular Modeling-Based Inclusion Mechanism and Stability Studies of Doxycycline and Hydroxypropyl-β-Cyclodextrin Complex for Ophthalmic Delivery
Author(s): Haohao Zhang; Meiwan Chen; Zixin He; Zhouhua Wang; Meimei Zhang; Zhouyang He; Qian Wan; Dan Liang; Michael A. Repka; Chuanbin Wu
Thermoreversible Nasal In situ Gel of Venlafaxine Hydrochloride: Formulation, Characterization, and Pharmacodynamic Evaluation
Author(s): Mandar J. Bhandwalkar; Amelia M. Avachat
The Experimental Evaluation and Molecular Dynamics Simulation of a Heat-Enhanced Transdermal Delivery System
Author(s): Daniel P. Otto; Melgardt M. Villiers
Development of Probiotic Tablets Using Microparticles: Viability Studies and Stability Studies
Author(s): J. P. Sousa Silva; Sérgio C. Sousa; Paulo Costa; Emília Cerdeira; Maria H. Amaral; José Sousa Lobo; Ana M. Gomes; Maria M. Pintado; Dina Rodrigues; Teresa Rocha-Santos; Ana C. Freitas
Characterization of a Sulfadiazine-Induced Lithiasis Calculus by Physicochemical Techniques
Author(s): C. Cuervo; J. González; V. Rives; M. A. Vicente
Evaluation of Meloxicam-Loaded Cationic Transfersomes as Transdermal Drug Delivery Carriers
Author(s): Sureewan Duangjit; Praneet Opanasopit; Theerasak Rojanarata; Tanasait Ngawhirunpat
Effect of Counterions on Physicochemical Properties of Prazosin Salts
Author(s): Lokesh Kumar; Chhuttan Lal Meena; Yogesh B. Pawar; Banrida Wahlang; Kulbhushan Tikoo; Rahul Jain; Arvind K. Bansal
Low-Viscosity Hydroxypropylcellulose (HPC) Grades SL and SSL: Versatile Pharmaceutical Polymers for Dissolution Enhancement, Controlled Release, and Pharmaceutical Processing
Author(s): Ashish Sarode; Peng Wang; Catherine Cote; David R. Worthen
Anti-inflammatory Effect of Seeds and Callus of Nigella sativa L. Extracts on Mix Glial Cells with Regard to Their Thymoquinone Content
Author(s): Mobina Alemi; Farzaneh Sabouni; Forough Sanjarian; Kamahldin Haghbeen; Saeed Ansari
Development of W/O Microemulsion for Transdermal Delivery of Iodide Ions
Author(s): Hao Lou; Ni Qiu; Catherine Crill; Richard Helms; Hassan Almoazen
Photodegradation and Stabilization of Betamethasone-17 Valerate in Aqueous/Organic Solvents and Topical Formulations
Author(s): Saif-ur-Rehman Khattak; Dilnawaz Shaikh; Iqbal Ahmad; Khan Usmanghani; Muhammad Ali Sheraz; Sofia Ahmed
Quantitative Characterization of Agglomerate Abrasion in a Tumbling Blender by Using the Stokes Number Approach
Author(s): Tofan A. Willemsz; Tien Thanh Nguyen; Ricardo Hooijmaijers; Henderik W. Frijlink; Herman Vromans; Kees Voort Maarschalk
Nanosuspension Based In Situ Gelling Nasal Spray of Carvedilol: Development, In Vitro and In Vivo Characterization
Author(s): Nilesh S. Saindane; Kunal P. Pagar; Pradeep R. Vavia
Investigating Gabapentin Polymorphism Using Solid-State NMR Spectroscopy
Author(s): Kassibla E. Dempah; Dewey H. Barich; Aditya M. Kaushal; Zhixin Zong; Salil D. Desai; Raj Suryanarayanan; Lee Kirsch; Eric J. Munson

In Themed Issue: Quality by Design: Case Studies and Scientific Foundations
Self-Associated Submicron IgG1 Particles for Pulmonary Delivery: Effects of Non-ionic Surfactants on Size, Shape, Stability, and Aerosol Performance
Author(s): Asha R. Srinivasan; Sunday A. Shoyele
Investigation on Side-Spray Fluidized Bed Granulation with Swirling Airflow
Author(s): Poh Mun Wong; Lai Wah Chan; Paul Wan Sia Heng
Nanolipidgel for Enhanced Skin Deposition and Improved Antifungal Activity
Author(s): Preeti Wavikar; Pradeep Vavia
Monitoring Blending of Pharmaceutical Powders with Multipoint NIR Spectroscopy
Author(s): Otto Scheibelhofer; Nikolaus Balak; Patrick R. Wahl; Daniel M. Koller; Benjamin J. Glasser; Johannes. G. Khinast
Design and Optimization of Sustained-Release Divalproex Sodium Tablets with Response Surface Methodology
Author(s): Farnaz Monajjemzadeh; Hamed Hamishehkar; Parvin Zakeri-Milani; Afsaneh Farjami; Hadi Valizadeh
Silver Sulfadiazine Nanosystems for Burn Therapy
Author(s): Meenakshi Venkataraman; Mangal Nagarsenker
Theophylline Cocrystals Prepared by Spray Drying: Physicochemical Properties and Aerosolization Performance
Author(s): Amjad Alhalaweh; Waseem Kaialy; Graham Buckton; Hardyal Gill; Ali Nokhodchi; Sitaram P. Velaga
Application of Quality by Design to the Process Development of Botanical Drug Products: A Case Study
Author(s): Lei Zhang; Binjun Yan; Xingchu Gong; Lawrence X. Yu; Haibin Qu
Thermal Stability and Decomposition Kinetic Studies of Acyclovir and Zidovudine Drug Compounds
Author(s): Mojtaba Shamsipur; Seied Mahdi Pourmortazavi; Ali Akbar Miran Beigi; Rouhollah Heydari; Mina Khatibi
Preparation and Evaluation of Orally Disintegrating Tablets Containing Taste-Masked Microcapsules of Berberine Hydrochloride
Author(s): Xuelian Hu; Yingbo Li; Engjuan Zhang; Xianzhu Wang; Mao Xing; Qian Wang; Jian Lei; Hua Huang
Development and Evaluation of α-Asarone Transdermal Patches Based on Hot-Melt Pressure-Sensitive Adhesives
Author(s): Zhenwei Yu; Yi Liang; Wenquan Liang
Cyclodextrin-Crosslinked Poly(Acrylic Acid): Adhesion and Controlled Release of Diflunisal and Fluconazole from Solid Dosage Forms
Author(s): Marguerite J. Kutyła; Michael W. Boehm; Jason R. Stokes; P. Nicholas Shaw; Nigel M. Davies; Ross P. McGeary; Jonathan Tuke; Benjamin P. Ross
Stability Enhancement of Drug Layered Pellets in a Fixed Dose Combination Tablet
Author(s): Matthew D. Burke; Xiaorong He; Chris Cook; Greg A. Petrov; Susan Long; Mark D. Coffin
Development, Characterization and Permeability Assessment Based on Caco-2 Monolayers of Self-Microemulsifying Floating Tablets of Tetrahydrocurcumin
Author(s): Namfa Sermkaew; Kamonthip Wiwattanawongsa; Wichan Ketjinda; Ruedeekorn Wiwattanapatapee
Liquid Proliposomes of Nimodipine Drug Delivery System: Preparation, Characterization, and Pharmacokinetics
Author(s): Chuandi Sun; Ji Wang; Jianping Liu; Lu Qiu; Wenli Zhang; Lei Zhang
Angular Circulation Speed of Tablets in a Vibratory Tablet Coating Pan
Author(s): Rahul Kumar; Carl Wassgren
Study of the Potential of Amphiphilic Conetworks Based on Poly(2-ethyl-2-oxazoline) as New Platforms for Delivery of Drugs with Limited Solubility
Author(s): Bistra Kostova; Krasimira Ivanova-Mileva; Dimitar Rachev; Darinka Christova
Soluble Itraconazole in Tablet Form Using Disordered Drug Delivery Approach: Critical Scale-up Considerations and Bio-equivalence Studies
Author(s): Shankar Swaminathan; Mayur Sangwai; Sharad Wawdhane; Pradeep Vavia
Good Cascade Impactor Practice (GCIP) and Considerations for “In-Use” Specifications
Author(s): S. C. Nichols; J. P. Mitchell; C. M. Shelton; D. L. Roberts
Effect of Surface Coating with Magnesium Stearate via Mechanical Dry Powder Coating Approach on the Aerosol Performance of Micronized Drug Powders from Dry Powder Inhalers
Author(s): Qi (Tony) Zhou; Li Qu; Thomas Gengenbach; Ian Larson; Peter J. Stewart; David A. V. Morton
A Novel Preparation Method for Organogels: High-Speed Homogenization and Micro-irradiation
Author(s): Evren Homan Gökçe; Aysu Yurdasiper; Emrah Korkmaz; Özgen Özer
Use of First Derivative of Displacement vs. Force Profiles to Determine Deformation Behavior of Compressed Powders
Author(s): Shadi F. Gharaibeh; Aktham Aburub
Experimental Analysis of Tablet Properties for Discrete Element Modeling of an Active Coating Process
Author(s): Sarah Just; Gregor Toschkoff; Adrian Funke; Dejan Djuric; Georg Scharrer; Johannes Khinast; Klaus Knop; Peter Kleinebudde
Thermally Triggered Mucoadhesive In Situ Gel of Loratadine: β-Cyclodextrin Complex for Nasal Delivery
Author(s): Reena M. P. Singh; Anil Kumar; Kamla Pathak
Development and Validation of a Discriminative Dissolution Test for Betamethasone Sodium Phosphate and Betamethasone Dipropionate Intramuscular Injectable Suspension
Author(s): Alice Simon; Vinícius Raphael Almeida Borges; Lucio Mendes Cabral; Valéria Pereira Sousa
Challenges in Detecting Magnesium Stearate Distribution in Tablets
Author(s): Satu Lakio; Balázs Vajna; István Farkas; Henri Salokangas; György Marosi; Jouko Yliruusi
Green Clay and Aloe Vera Peel-Off Facial Masks: Response Surface Methodology Applied to the Formulation Design
Author(s): André O’Reilly Beringhs; Julia Macedo Rosa; Hellen Karine Stulzer; Rosane Maria Budal; Diva Sonaglio
Design and In Vitro Evaluation of Finasteride-Loaded Liquid Crystalline Nanoparticles for Topical Delivery
Author(s): Thiagarajan Madheswaran; Rengarajan Baskaran; Raj Kumar Thapa; Jeong Yeon Rhyu; Hye Yoon Choi; Jong Oh Kim; Chul Soon Yong; Bong Kyu Yoo
Phase Behaviour and Formation of Fatty Acid Esters Nanoemulsions Containing Piroxicam
Author(s): Nursyamsyila Mat Hadzir; Mahiran Basri; Mohd Basyaruddin Abdul Rahman; Abu Bakar Salleh; Raja Noor Zaliha Raja Abdul Rahman; Hamidon Basri
Amorphous Solid Dispersions of Sulfonamide/Soluplus® and Sulfonamide/PVP Prepared by Ball Milling
Author(s): Vincent Caron; Yun Hu; Lidia Tajber; Andrea Erxleben; Owen I. Corrigan; Patrick McArdle; Anne Marie Healy
Assessment of Isomalt for Colon-Specific Delivery and Its Comparison with Lactulose
Author(s): Mohamed Hassan G. Dehghan; V. Rama Mohan Gupta; Shaikh Mohammed Asif; Yusrida Darwis; Mohammad Rizwan; Veenu Piyush Mundada
Correlation between Nasal Membrane Permeability and Nasal Absorption Rate
Author(s): Hefei Zhang; Chih-Wei Lin; Maureen D. Donovan
Design, Characterization, and In Vitro Evaluation of Antifungal Polymeric Films
Author(s): Daniel A. Real; María V. Martinez; Agustín Frattini; Marina Soazo; Alicia G. Luque; Marisa S. Biasoli; Claudio J. Salomon; Alejandro C. Olivieri; Darío Leonardi
Adsorption and Degradation of Doxorubicin from Aqueous Solution in Polypropylene Containers
Author(s): Darren C. Wu; Clyde M. Ofner
Lyophilized Oral Sustained Release Polymeric Nanoparticles of Nateglinide
Author(s): Mohammad Kaleemuddin; Prathima Srinivas
Application of Near-Infrared Spectroscopy in Real-Time Monitoring of Product Attributes of Ribbed Roller Compacted Flakes
Author(s): Asim Kumar Samanta; Atul D. Karande; Ka Yun Ng; Paul Wan Sia Heng

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