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Author: Vijay Kumar, Michael K. Taylor, Amit Mehrotra, William C. Stagner
Keywords: continuous granulation-drying-milling,focused beam reflectance measurement (FBRM),process analytical technology (PAT),real-time particle size measurement Summary: determined by FBRM and nested sieve analysis, respectively. An inline FBRM probe placed below the Comil-generated chord lengths and CLD data at designated times the timing of the FBRM determinations.
AAPS PharmSciTech; Vol. 14 Number 2, Jun 2013;Published Date:05/31/2013; DOI: 10.1208/s12249-013-9934-4
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Author: Ahmed S. Zidan, Ziyaur Rahman, Mansoor A. Khan
Keywords: biodegradable polymers,FBRM and PVM,Lasentec,microparticles,particle sizing Summary: beam reflectance (FBRM) system for
As indicated from the chord count data, FBRM
This study illustrated the utility of FBRM and PVM in
The AAPS Journal; Vol. 12 Number 3, Sep 2010;Published Date:08/31/2010; DOI: 10.1208/s12248-010-9184-2
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Author: Ai Tee Tok, Xueping Goh, Wai Kiong Ng, Reginald B. H. Tan
Keywords: acoustic emission,FBRM,granulation,near-infra red,PAT Summary: chord length distribution and chord count (from FBRM), absorption spectra (from NIR) and average
dependent on optical signals, the sensitivities of the FBRM and NIR techniques were susceptible to
acoustic emission; FBRM; granulation; near-infra red; PAT.
AAPS PharmSciTech; Vol. 9 Number 4, Dec 2008;Published Date:11/30/2008; DOI: 10.1208/s12249-008-9145-6
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Author: Farhad Tajarobi, Susanna Abrahmsén-Alami, Magnus Hansen, Anette Larsson
Keywords: drug load,HPMC,percolation threshold,release robustness,solubility Summary: Pharmaceutical Research, Vol. 26, No. 6, June 2009 ( # 2009)
DOI: 10.1007/s11095-009-9861-y
Research Paper
The Impact of Dose and Solubility of Additives on the Release from HPMC
Matrix Tablets--Identifying
Pharmaceutical Research; Vol. 26 Number 6, Jun 2009;Published Date:05/31/2009; DOI: 10.1007/s11095-009-9861-y
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Author: Tero Närvänen, Kari Seppälä, Osmo Antikainen, Jouko Yliruusi
Keywords: fluid bed granulation,image analysis,on-line particle size,topography Summary: beam reflectance method (FBRM) and spatial filtering
The FBRM has been largely applied in crystallization
AAPS PharmSciTech; Vol. 9 Number 1, Mar 2008;Published Date:02/29/2008; DOI: 10.1208/s12249-008-9043-y
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Author: Cheng Tong, Susan S. D’Souza, Jan E. Parker, Tahseen Mirza
Keywords: AAPS,commentary,dissolution,process analytical technology,quality by design,workshop Summary: Pharmaceutical Research, Vol. 24, No. 9, September 2007 (# 2007)
DOI: 10.1007/s11095-007-9280-x
Commentary
Commentary on AAPS Workshop
Dissolution Testing for the Twenty-first Century: Linking Critical
Pharmaceutical Research; Vol. 24 Number 9, Sep 2007;Published Date:08/31/2007; DOI: 10.1007/s11095-007-9280-x
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Author: Tero Närvänen, Osmo Antikainen, Jouko Yliruusi
Keywords: fluid bed granulation,granule growth,modeling,particle size distribution,process analytical technology (PAT) Summary: AAPS PharmSciTech, Vol. 10, No. 4, December 2009 ( # 2009)
DOI: 10.1208/s12249-009-9310-6
Research Article
Predicting Particle Size During Fluid Bed Granulation Using Process
Measurement Data
Tero
AAPS PharmSciTech; Vol. 10 Number 4, Dec 2009;Published Date:11/30/2009; DOI: 10.1208/s12249-009-9310-6
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Author: L. W. Chan, L. H. Tan, Paul W. S. Heng
Keywords: laser diffraction,particle size,process analytical technology,spray drying Summary: AAPS PharmSciTech, Vol. 9, No. 1, March 2008 (# 2007)
DOI: 10.1208/s12249-007-9011-y
Research Article
Themed Issue: Process Analytical Technology
Guest Editor: Ajaz Hussain
Process Analytical Technology:
AAPS PharmSciTech; Vol. 9 Number 1, Mar 2008;Published Date:02/29/2008; DOI: 10.1208/s12249-007-9011-y
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