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Text: FBRM
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Real-Time Particle Size Analysis Using Focused Beam Reflectance Measurement as a Process Analytical Technology Tool for a Continuous Granulation–Drying–Milling Process
Author: Vijay Kumar, Michael K. Taylor, Amit Mehrotra, William C. Stagner

Keywords: continuous granulation-drying-milling,focused beam reflectance measurement (FBRM),process analytical technology (PAT),real-time particle size measurement
Summary: determined by FBRM and nested sieve analysis, respectively. An inline FBRM probe placed below the Comil-generated chord lengths and CLD data at designated times the timing of the FBRM determinations.

AAPS PharmSciTech; Vol. 14 Number 2, Jun 2013;Published Date:05/31/2013; DOI: 10.1208/s12249-013-9934-4
Online Monitoring of PLGA Microparticles Formation Using Lasentec Focused Beam Reflectance (FBRM) and Particle Video Microscope (PVM)
Author: Ahmed S. Zidan, Ziyaur Rahman, Mansoor A. Khan

Keywords: biodegradable polymers,FBRM and PVM,Lasentec,microparticles,particle sizing
Summary: beam reflectance (FBRM) system for As indicated from the chord count data, FBRM This study illustrated the utility of FBRM and PVM in

The AAPS Journal; Vol. 12 Number 3, Sep 2010;Published Date:08/31/2010; DOI: 10.1208/s12248-010-9184-2
Monitoring Granulation Rate Processes Using Three PAT Tools in a Pilot-Scale Fluidized Bed
Author: Ai Tee Tok, Xueping Goh, Wai Kiong Ng, Reginald B. H. Tan

Keywords: acoustic emission,FBRM,granulation,near-infra red,PAT
Summary: chord length distribution and chord count (from FBRM), absorption spectra (from NIR) and average dependent on optical signals, the sensitivities of the FBRM and NIR techniques were susceptible to acoustic emission; FBRM; granulation; near-infra red; PAT.

AAPS PharmSciTech; Vol. 9 Number 4, Dec 2008;Published Date:11/30/2008; DOI: 10.1208/s12249-008-9145-6
The Impact of Dose and Solubility of Additives on the Release from HPMC Matrix Tablets—Identifying Critical Conditions
Author: Farhad Tajarobi, Susanna Abrahmsén-Alami, Magnus Hansen, Anette Larsson

Keywords: drug load,HPMC,percolation threshold,release robustness,solubility
Summary: Pharmaceutical Research, Vol. 26, No. 6, June 2009 ( # 2009) DOI: 10.1007/s11095-009-9861-y Research Paper The Impact of Dose and Solubility of Additives on the Release from HPMC Matrix Tablets--Identifying

Pharmaceutical Research; Vol. 26 Number 6, Jun 2009;Published Date:05/31/2009; DOI: 10.1007/s11095-009-9861-y
A New Rapid On-Line Imaging Method to Determine Particle Size Distribution of Granules
Author: Tero Närvänen, Kari Seppälä, Osmo Antikainen, Jouko Yliruusi

Keywords: fluid bed granulation,image analysis,on-line particle size,topography
Summary: beam reflectance method (FBRM) and spatial filtering The FBRM has been largely applied in crystallization

AAPS PharmSciTech; Vol. 9 Number 1, Mar 2008;Published Date:02/29/2008; DOI: 10.1208/s12249-008-9043-y
Commentary on AAPS Workshop
Author: Cheng Tong, Susan S. D’Souza, Jan E. Parker, Tahseen Mirza

Keywords: AAPS,commentary,dissolution,process analytical technology,quality by design,workshop
Summary: Pharmaceutical Research, Vol. 24, No. 9, September 2007 (# 2007) DOI: 10.1007/s11095-007-9280-x Commentary Commentary on AAPS Workshop Dissolution Testing for the Twenty-first Century: Linking Critical

Pharmaceutical Research; Vol. 24 Number 9, Sep 2007;Published Date:08/31/2007; DOI: 10.1007/s11095-007-9280-x
Predicting Particle Size During Fluid Bed Granulation Using Process Measurement Data
Author: Tero Närvänen, Osmo Antikainen, Jouko Yliruusi

Keywords: fluid bed granulation,granule growth,modeling,particle size distribution,process analytical technology (PAT)
Summary: AAPS PharmSciTech, Vol. 10, No. 4, December 2009 ( # 2009) DOI: 10.1208/s12249-009-9310-6 Research Article Predicting Particle Size During Fluid Bed Granulation Using Process Measurement Data Tero

AAPS PharmSciTech; Vol. 10 Number 4, Dec 2009;Published Date:11/30/2009; DOI: 10.1208/s12249-009-9310-6
Process Analytical Technology: Application to Particle Sizing in Spray Drying
Author: L. W. Chan, L. H. Tan, Paul W. S. Heng

Keywords: laser diffraction,particle size,process analytical technology,spray drying
Summary: AAPS PharmSciTech, Vol. 9, No. 1, March 2008 (# 2007) DOI: 10.1208/s12249-007-9011-y Research Article Themed Issue: Process Analytical Technology Guest Editor: Ajaz Hussain Process Analytical Technology:

AAPS PharmSciTech; Vol. 9 Number 1, Mar 2008;Published Date:02/29/2008; DOI: 10.1208/s12249-007-9011-y
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