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Novel Cyclopeptides for the Design of MMP Directed Delivery Devices: A Novel Smart Delivery Paradigm
Author: El-Farouck Moustoifa, Mohamed-Anis Alouini, Arnaud Salaün, Thomas Berthelot, Aghleb Bartegi, Sandra Albenque-Rubio, Gérard Déléris

Keywords: cancer,cyclic peptide,delivery device,fluorescent substrate,MMP
Summary: Purpose Matrix metalloproteinases (MMP) are a family of MMP pies is correlated with MMP-2 and MMP-9 over-expression

Pharmaceutical Research; Vol. 27 Number 8, Aug 2010;Published Date:07/31/2010; DOI: 10.1007/s11095-010-0164-0
Polydopamine-Based Surface Modification for the Development of Peritumorally Activatable Nanoparticles
Author: Emily Gullotti, Joonyoung Park, Yoon Yeo

Keywords: dopamine polymerization,PEG cleavage,polymeric nanoparticles,surface modification,TAT peptide
Summary: NPs and MMP-2pre-treated PANPs showed relatively good cellular uptake compared to PLGA NPs, MMP-2-n in response to MMP-2 were successfully created by dual modification of PLGA NPs using dopamine poly of PEG and MMP-substrate via dopamine polymerization (PLGA-pDA-TAT/ MMP-substrate PEG NPs) pDA Poly

; DOI: 10.1007/s11095-013-1039-y
Composite Hydrogel Formulations of Stratifin to Control MMP-1 Expression in Dermal Fibroblasts
Author: Elham Rahmani-Neishaboor, John Jackson, Helen Burt, Aziz Ghahary

Keywords: hydrogel,hypertrophic scarring,matrix metalloproteinase,microspheres,stratifin
Summary: loproteinase-1 (MMP-1) in dermal fibroblasts. and stimulate the expression of MMP-1 in a sustained manner over the late stages of wound healing the levels of MMP-1

Pharmaceutical Research; Vol. 26 Number 8, Aug 2009;Published Date:07/31/2009; DOI: 10.1007/s11095-009-9916-0
Matrix Metalloproteinase Gene Delivery for Liver Fibrosis
Author: Yuji Iimuro, David A. Brenner

Keywords: gene delivery,hepatic stellate cells,liver fibrosis,MMP,TIMP
Summary: gene delivery; hepatic stellate cells; liver fibrosis; MMP; TIMP. matrix metalloproteinase (MMP)-1 in humans and MMP-13 sion of MMP-1 or MMP-13 is very limited, whereas that of

Pharmaceutical Research; Vol. 25 Number 2, Feb 2008;Published Date:01/31/2008; DOI: 10.1007/s11095-007-9311-7
Effects of Molecular Weight and Loading on Matrix Metalloproteinase-2 Mediated Release from Poly(Ethylene Glycol) Diacrylate Hydrogels
Author: Amy E. Ross, Mary Y. Tang, Richard A. Gemeinhart

Keywords: cancer,chemotherapy,controlled drug delivery,enzyme-triggered drug delivery,matrix metalloproteinase-2,poly(ethylene glycol) diacrylate, hydrogel
Summary: We investigated MMP-2 entry and optimized parameters of the drug delivery system. the dimensions of MMP-2 and PEGDA 10,000 and PEGDA 20,000 hydrogels having mesh sizes larger than M Purified MMP-2 increased release of peptide fragment compared to buffer at several loading concentra

The AAPS Journal; Vol. 14 Number 3, Sep 2012;Published Date:08/31/2012; DOI: 10.1208/s12248-012-9356-3
Bioreducible Crosslinked Polyelectrolyte Complexes for MMP-2 siRNA Delivery into Human Vascular Smooth Muscle Cells
Author: Dokyoung Lee, Dongkyu Kim, Hyejung Mok, Ji Hoon Jeong, Donghoon Choi, Sun Hwa Kim

Keywords: bioreducible crosslinked polyplexes,human vascular smooth muscle cells,matrix metalloproteinase-2,small interfering RNA
Summary: (MMP-2) siRNA under serum conditions. The MMP-2 levels in the conditioned medium were examined using gelatin zymography. slight decrease in MMP-2 gene silencing activity in hSMCs due to the insufficient redox potential.

Pharmaceutical Research; Vol. 29 Number 8, Aug 2012;Published Date:07/31/2012; DOI: 10.1007/s11095-012-0750-4
FoxM1 is a Novel Target of a Natural Agent in Pancreatic Cancer
Author: Zhiwei Wang, Aamir Ahmad, Sanjeev Banerjee, Asfar Azmi, Dejuan Kong, Yiwei Li, Fazlul H. Sarkar

Keywords: FoxM1,genistein,invasion,pancreatic cancer,proliferation
Summary: MMP-9, and VEGF, resulting in the inhibition of pancreatic FoxM1, MMP-9, VEGF, Survivin and cdc25A were

Pharmaceutical Research; Vol. 27 Number 6, Jun 2010;Published Date:05/31/2010; DOI: 10.1007/s11095-010-0106-x
Designing 3D Photopolymer Hydrogels to Regulate Biomechanical Cues and Tissue Growth for Cartilage Tissue Engineering
Author: Stephanie J. Bryant, Garret D. Nicodemus, Idalis Villanueva

Keywords: cartilage,hydrogel,photopolymerization,tissue engineering
Summary: Pharmaceutical Research, Vol. 25, No. 10, October 2008 (# 2008) DOI: 10.1007/s11095-008-9619-y Research Paper Designing 3D Photopolymer Hydrogels to Regulate Biomechanical Cues and Tissue Growth for

Pharmaceutical Research; Vol. 25 Number 10, Oct 2008;Published Date:09/30/2008; DOI: 10.1007/s11095-008-9619-y
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