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Author: Andrei Ponta, Younsoo Bae
Keywords: controlled drug delivery,functional block copolymers,pH-sensitive drug release,polymer micelles,tunable drug release
Summary: PEG-poly(amino acid) Block Copolymer Micelles for Tunable
spacer-modified hydrazone drug-binding linkers. phobic and toxic drug payloads as well as functional groups
Pharmaceutical Research; Vol. 27 Number 11, Nov 2010;Published Date:10/31/2010; DOI: 10.1007/s11095-010-0120-z
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Author: Stéphanie Deshayes, Victor Maurizot, Marie-Claude Clochard, Cécile Baudin, Thomas Berthelot, Stéphane Esnouf, Didier Lairez, Michel Moenner, Gérard Déléris
Keywords: angiogenesis,“click” chemistry,cyclo-peptide,nanoparticles,PVDF,tumor targeting
Summary: also as Flt-1) and VEGFR-2 (known also as KDR) (5�7) laboratory, we have synthesized a 17-amino acid molecule
applications have been as well reported, such as membranes
Pharmaceutical Research; Vol. 28 Number 7, Jul 2011;Published Date:06/30/2011; DOI: 10.1007/s11095-011-0398-5
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Author: Yun Bai, Wei-Chiang Shen
Keywords: G-CSF,linker peptides,oral delivery,recombinant fusion protein,transferrin
Summary: thelia, as indicated by its myelopoietic activity when orally
peptide with the amino acid sequence of A(EAAAK)2A; H3, linker
DNA sequence of each spacer-containing plasmid was
Pharmaceutical Research; Vol. 23 Number 9, Sep 2006;Published Date:08/31/2006; DOI: 10.1007/s11095-006-9059-5
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Author: Aijun Tang, Pavla Kopečková, Jindřich Kopeček
Keywords: HPMA copolymer conjugates,epitope,CD21 receptor,binding affinity,cytotoxicity,lymphocytes
Summary: solid tumors as a result of enhanced permeability and a re- to act as biorecognition sites for the B-cell CD21 receptor. rather new approach is to use receptor-binding epitopes as
Pharmaceutical Research; Vol. 20 Number 3, Mar 2003;Published Date:02/28/2003; DOI: 10.1023/A:1022639701388
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Author: Sreeja Jayant, Jayant J. Khandare, Yang Wang, Ajay P. Singh, Nicholi Vorsa, Tamara Minko
Keywords: doxorubicin,intracellular delivery,prodrugs,sialic acid,targeting
Summary: targeting moiety), doxorubicin (DOX), citric acid (multifunctional spacer) and poly(ethylene glycol) through a citric acid spacer and characterized by proton nuclear magnetic resonance (1HNMR), matrix- Second, it works as a penetration
Pharmaceutical Research; Vol. 24 Number 11, Nov 2007;Published Date:10/31/2007; DOI: 10.1007/s11095-007-9406-1
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Author: Giridhar Thiagarajan, Abhijit Ray, Alexander Malugin, Hamidreza Ghandehari
Keywords: PAMAM dendrimer,camptothecin,drug delivery,colorectal cancer
Summary: 4-dimethyl amino pyridine
deoxyribonucleic acid
As a step towards that goal we
Pharmaceutical Research; Vol. 27 Number 11, Nov 2010;Published Date:10/31/2010; DOI: 10.1007/s11095-010-0179-6
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Author: Darren C. Wu, Christopher R. Cammarata, Hyun Joo Park, Brian T. Rhodes, Clyde M. Ofner
Keywords: acid labile hydrazone,cell growth inhibition,doxorubicin,drug delivery,gelatin,HPLC-SEC,macromolecular conjugates
Summary: systems such as liposomes (2), synthetic copolymers of N-(2-hydroxypropyl)methacrylamide (HPMA) (3, a polyglutamic acid carrier used with paclitaxol failed to demonstrate improved overall survival in characterization, as well as its in vitro drug release, and cancer cell growth inhibition are repor
; DOI: 10.1007/s11095-013-1065-9
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Author: Molly E. Martin, Kevin G. Rice
Keywords: Peptide-guided gene delivery,fusogenic peptide,nuclear localization,targeted delivery,proteasome
Summary: The use of peptides as gene deliv- rely on viral vectors, such as adenoviruses, adeno- associated PLL is a synthetic repeat of the amino acid
The AAPS Journal; Vol. 9 Number 1, Mar 2007;Published Date:02/28/2007; DOI: 10.1208/aapsj0901003
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