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Author: Simon Bates, George Zografi, David Engers, Kenneth Morris, Kieran Crowley, Ann Newman
Keywords: amorphous,CRN,disorder,disordered nanocrystalline,glass,pair distribution function (PDF),RCP,Rietveld,total scattering,X-ray powder diffraction (XRPD)
Summary: The purpose of this paper is to provide a physical description of the amorphous state for
The X-ray amorphous powder diffraction patterns of microcrystalline cellulose, The observation of X-ray amorphous powder patterns may indicate the presence of amorphous,
Pharmaceutical Research; Vol. 23 Number 10, Oct 2006;Published Date:09/30/2006; DOI: 10.1007/s11095-006-9086-2
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Author: Paul T. Whiteside, Shen Y. Luk, Claire E. Madden-Smith, Paul Turner, Nikin Patel, Michael W. George
Keywords: amorphous,deuteration,lactose,quantification,Raman
Summary: for the detection and quantification of low levels of amorphous lactose in formulations. Samples containing different proportions of amorphous and crystalline lactose were prepared. using Raman spectroscopy where the ratio of Raman bands associated with crystalline and amorphous
Pharmaceutical Research; Vol. 25 Number 11, Nov 2008;Published Date:10/31/2008; DOI: 10.1007/s11095-008-9682-4
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Author: Bruno C. Hancock, Michael Parks
Keywords: amorphous,crystal,solubility,dissolution
Summary: amorphous pharmaceutical materials when compared to their crystal- The thermal properties of several drugs in their amorphous
amorphous form of a drug presents a more significant challenge
Pharmaceutical Research; Vol. 17 Number 4, Apr 2000;Published Date:03/31/2000; DOI: 10.1023/A:1007516718048
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Author: Sarah E Hogan, Graham Buckton
Keywords: amorphous lactose,quantification,near infrared spectroscopy,dynamic vapor sorption
Summary: In addition, amorphous material is thermody- RH), to undergo changes in its amorphous structure, or to
Quantification of amorphous contents of materials is
Pharmaceutical Research; Vol. 18 Number 1, Jan 2001;Published Date:12/31/2000; DOI: 10.1023/A:1011091113734
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Author: Sharad B. Murdande, Michael J. Pikal, Ravi M. Shanker, Robin H. Bogner
Keywords: amorphous,crystal,dissolution,re-crystallization,solubility,solubility enhancement,solute activity in amorphous,thermodynamics
Summary: cantly higher, it was observed that the amorphous drug
amorphous forms of nine insoluble drugs with a wide range of
Methods Thermal properties of amorphous and crystalline
; DOI: 10.1007/s11095-010-0269-5
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Author: David E. Alonzo, Geoff G. Z. Zhang, Deliang Zhou, Yi Gao, Lynne S. Taylor
Keywords: amorphous,dissolution,felodipine,indomethacin,metastable,polymer,supersaturation
Summary: To investigate the underlying physical processes taking place during dissolution of amorphous
Concentration-time profiles were monitored during dissolution of the model amorphous
37�C. The amorphous solid was found to crystallize rapidly at both temperatures upon exposure to the
Pharmaceutical Research; Vol. 27 Number 4, Apr 2010;Published Date:03/31/2010; DOI: 10.1007/s11095-009-0021-1
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Author: Katsuhiko Masuda, Sachio Tabata, Yasuyuki Sakata, Tetsuo Hayase, Etsuo Yonemochi, Katsuhide Terada
Keywords: amorphous indomethacin,amorphous salicin,molecular mobility,solid-state 13C NMR,spin-lattice relaxation times (T1c)
Summary: The purpose of the current study was to evaluate the molecular mobility of amorphous
value of amorphous indomethacin indicated that 73% of carbons were in a state of
amorphous indomethacin; amorphous salicin; molecular mobility; solid-state 13C NMR;
Pharmaceutical Research; Vol. 22 Number 5, May 2005;Published Date:04/30/2005; DOI: 10.1007/s11095-005-2597-4
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Author: Lei Zhu, Janan Jona, Karthik Nagapudi, Tian Wu
Keywords: amorphous solids,coating,crystallization kinetic,griseofulvin,surface-enhanced crystallization
Summary: Purpose To study crystal growth rates of amorphous griseo- crystallization of amorphous solids. KEY WORDS amorphous solids
Pharmaceutical Research; Vol. 27 Number 8, Aug 2010;Published Date:07/31/2010; DOI: 10.1007/s11095-010-0140-8
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