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Author: Mahesh N. Samtani, Matthias Schwab, Peter W. Nathanielsz, William J. Jusko
Keywords: corticosteroid,fetus,p-glycoprotein,pharmacokinetics,pregnancy
Summary: Comprehensive compartmental pharmacokinetic analy- moment and compartmental methods for obtaining all the
Area/Moment analysis, compartmental modeling, and allo-
Pharmaceutical Research; Vol. 21 Number 12, Dec 2004;Published Date:11/30/2004; DOI: 10.1007/s11095-004-7681-7
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Author: Danielle N. McLennan, Christopher J. H. Porter, Glenn A. Edwards, Anne C. Heatherington, Steven W. Martin, Susan A. Charman
Keywords: darbepoetin alfa,lymph,protein delivery,protein pharmacokinetics,subcutaneous injection
Summary: Pharmaceutical Research, Vol. 23, No. 9, September 2006 (# 2006)
DOI: 10.1007/s11095-006-9064-8
Research Paper
The Absorption of Darbepoetin Alfa Occurs Predominantly via the Lymphatics
Following Subcutaneous
Pharmaceutical Research; Vol. 23 Number 9, Sep 2006;Published Date:08/31/2006; DOI: 10.1007/s11095-006-9064-8
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Author: Susan Grange, Nicholas H. G. Holford, Theodor W. Guentert
Keywords: L-dopa,3-O-methyldopa,benserazide,PK drug-drug interaction,amino acid decarboxylase
Summary: Compartmental modelling
terized by noncompartmental analysis and a compartmental model
The compartmental model allowed an
Pharmaceutical Research; Vol. 18 Number 8, Aug 2001;Published Date:07/31/2001; DOI: 10.1023/A:1010935228654
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Author: Amparo de la Penña, Teresa Dalla Costa, James D. Talton, Edelgard Rehak, Jens Gross, Ursula Thyroff-Friesinger, Alistair I. Webb, Markus Müller, Hartmut Derendorf
Keywords: pharmacokinetics,free tissue concentrations,microdialysis,muscle,lung,rat,cefaclor,β-lactam antibiotics
Summary: compartmental and compartmental pharmacokinetic ap-
Pharmaceutical Research; Vol. 18 Number 9, Sep 2001;Published Date:08/31/2001; DOI: 10.1023/A:1013042128791
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Author: C. Andrew Boswell, Daniela Bumbaca, Paul J. Fielder, Leslie A. Khawli
Keywords: antibody,biodistribution,compartmental analysis,pharmacokinetics,physiology
Summary: 612-618 Compartmental Tissue Distribution of Antibody Therapeutics: of antibodies at a compartmental level is highlighted, including a brief overview of receptor occup compartmental analysis
The AAPS Journal; Vol. 14 Number 3, Sep 2012;Published Date:08/31/2012; DOI: 10.1208/s12248-012-9374-1
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Author: Lucila Garcia-Contreras, Tülin Morçöl, Steve J. D. Bell, Anthony J. Hickey
Keywords: pulmonary delivery,insulin,CAP-PEG particles,pharmacokinetics,pharmacodynamics
Summary: analyzed by compartmental and non-compartmental PK analysis suggested that insulin adminis- PD analysis showed that smaller areas
The AAPS Journal; Vol. 5 Number 2, Jun 2003;Published Date:05/31/2003; DOI: 10.1208/ps050209
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Author: Weili Huang, Sau Lawrence Lee, Lawrence X. Yu
Keywords: advanced compartmental absorption and transit (ACAT) model,advanced dissolution, absorption, and metabolism (ADAM) model,compartmental model,dispersion model,oral drug absorption
Summary: The compartmental models
include the compartmental absorption and transit model; Grass model; gastrointestinal transit absorp model; advanced compartmental absorption and transit model; and advanced dissolution, absorption, an
The AAPS Journal; Vol. 11 Number 2, Jun 2009;Published Date:05/31/2009; DOI: 10.1208/s12248-009-9098-z
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Author: Leonid Kagan, Anson K. Abraham, John M. Harrold, Donald E. Mager
Keywords: allometry,interferon,nonlinear pharmacokinetics,receptor binding,target-mediated drug disposition
Summary: models have been successfully applied for the analysis of
For initial data evaluation, a non-compartmental data
analysis was performed.
Pharmaceutical Research; Vol. 27 Number 5, May 2010;Published Date:04/30/2010; DOI: 10.1007/s11095-010-0098-6
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