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Author: Mark Staples, Karen Daniel, Michael J. Cima, Robert Langer
Keywords: combination products,drug delivery,integrated medical systems,microelectromechanical systems (MEMS),nano-electromechanical systems (NEMS)
Summary: Micro- and nano-electromechanical systems (MEMS and NEMS)-based drug delivery devices
Innovative delivery devices
delivery device constructed using MEMS-
Pharmaceutical Research; Vol. 23 Number 5, May 2006;Published Date:04/30/2006; DOI: 10.1007/s11095-006-9906-4
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Author: Dakshina M. Chilukuri, Jaymin C. Shah
Keywords: local delivery,prosthetic device,biofilm infection,surgical wound infection,vancomycin,implants,antibiotic,pharmacokinetics,efficacy,glyceryl monostearate
Summary: In vivo efficacy was studied by evaluation of the wound site and the prosthetic device upon
delivery system in a prosthetic device related biofilm infection model. local delivery; prosthetic device; biofilm infection; surgical wound infection; vancomy-
Pharmaceutical Research; Vol. 22 Number 4, Apr 2005;Published Date:03/31/2005; DOI: 10.1007/s11095-005-2497-7
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Author: Barbara G. Stubbe, Stefaan C. De Smedt, Joseph Demeester
Keywords: drug delivery,pulsatile programmed drug delivery,pulsed drug release,vaccine delivery
Summary: Programmed Polymeric Devices" for Pulsed Drug Delivery
drug delivery; pulsatile programmed drug delivery; pulsed drug release; vaccine deliv- grammed drug delivery devices that are able to generate more
Pharmaceutical Research; Vol. 21 Number 10, Oct 2004;Published Date:09/30/2004; DOI: 10.1023/B:PHAM.0000045223.45400.01
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Author: Deepak Tiwari, Robert Sause, Parshotam L. Madan, David Goldman
Keywords: polyox,bioadhesion,compression molding,buccal patch,polyethyleneoxide
Summary: Delivery Device Formulations buccal bioadhesive drug (BBD) delivery device devices were evaluated for their elasticity, in vitro
The AAPS Journal; Vol. 1 Number 3, Sep 1999;Published Date:08/31/1999; DOI: 10.1208/ps010313
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Author: Siôn A. Coulman, James C. Birchall, Aneesh Alex, Marc Pearton, Bernd Hofer, Conor O’Mahony, Wolfgang Drexler, Boris Považay
Keywords: in vivo,microneedle,optical coherence tomography,skin,transdermal
Summary: for all studied devices, microconduit dimensions are markedly
in the future development of microneedle devices and other
relevant to drug delivery and device safety.
; DOI: 10.1007/s11095-010-0167-x
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Author: Seyed Mojtaba Taghizadeh, Arezou Soroushnia, Fatemeh Mohamadnia
Keywords: adhesion properties,fentanyl,peel strength,pressure-sensitive adhesive,skin permeation,tack,transdermal drug delivery system
Summary: TDDSs on skin permeation and in vitro drug release from devices were evaluated using a hydrodynami- In double- and single-layer devices after 1 and 3 h, respectively, drug release
Generally, in this type of device, the delivery rate diminishes
AAPS PharmSciTech; Vol. 11 Number 1, Mar 2010;Published Date:02/28/2010; DOI: 10.1208/s12249-009-9366-3
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Author: Scott A. Burton, Chin-Yee Ng, Ryan Simmers, Craig Moeckly, David Brandwein, Tom Gilbert, Nathan Johnson, Ken Brown, Tesha Alston, Gayatri Prochnow, Kris Siebenaler, Kris Hansen
Keywords: transdermal drug delivery,microneedles,intradermal,hollow microstructures,MTS
Summary: intradermal delivery of up to 1.5 mL of formulation using a hol ow
microneedle delivery device designed for self-application. One-mL deliveries of commercial
; DOI: 10.1007/s11095-010-0177-8
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Author: Sau Lawrence Lee, Wallace P. Adams, Bing V. Li, Dale P. Conner, Badrul A. Chowdhury, Lawrence X. Yu
Keywords: bioequivalence (BE),dry powder inhaler (DPI),locally acting drugs,particle size distribution,single inhalation (actuation) content
Summary: Thus, BE of these drug/device combination products is established
These aspects include comparability in device resistance and equivalence in in vitro
Their drug delivery and intended action do
The AAPS Journal; Vol. 11 Number 3, Sep 2009;Published Date:08/31/2009; DOI: 10.1208/s12248-009-9121-4
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