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Text: lyophilization
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Effect of Lyophilization and Freeze-thawing on the Stability of siRNA-liposome Complexes
Author: Preeti Yadava, Melissa Gibbs, Carlos Castro, Jeffrey A. Hughes

Keywords: DLS,FACS,freeze-thaw,liposomes,lyophilization,siRNA
Summary: The purpose of this research was to describe the application of lyophilization in the delivery of to either lyophilization or freeze thaw lyophilization process did not alter siRNA's intrinsic biological activity as was evident by the abi

AAPS PharmSciTech; Vol. 9 Number 2, Jun 2008;Published Date:05/31/2008; DOI: 10.1208/s12249-007-9000-1
In-Situ Near-Infrared Spectroscopy Monitoring of the Lyophilization Process
Author: Mikael Brülls, Staffan Folestad, Anders Sparén, Anders Rasmuson

Keywords: lyophilization,freeze-drying,process,NIR,monitoring,in-situ
Summary: the global end point of the lyophilization process, but the material and lyophilization apparatus, which is a laborious tion of samples being lyophilized in a special lyophilization stage

Pharmaceutical Research; Vol. 20 Number 3, Mar 2003;Published Date:02/28/2003; DOI: 10.1023/A:1022680810474
Lyophilization of Protein-Loaded Polyelectrolyte Microcapsules
Author: Marie-Luce Temmerman, Joanna Rejman, Johan Grooten, Thomas Beer, Chris Vervaet, Jo Demeester, Stefaan C. Smedt

Keywords: drug delivery,encapsulation,layer-by-layer,lyophilization,microcapsules
Summary: Purpose To evaluate if lyophilization can be used to obtain a lyophilization nicity after lyophilization was evaluated in vitro by a T-cell

Pharmaceutical Research; Vol. 28 Number 7, Jul 2011;Published Date:06/30/2011; DOI: 10.1007/s11095-011-0411-z
Liposomal dry powders as aerosols for pulmonary delivery of proteins
Author: Dongmei Lu, Anthony J. Hickey

Keywords: protein,liposome,lyophilization,dry powders,aerosol,pulmonary delivery
Summary: After lyophilization GUS activity after lyophilization and 36% of GUS amount, on lyophilization of protein liposome formulations are re-

AAPS PharmSciTech; Vol. 6 Number 4, Dec 2005;Published Date:11/30/2005; DOI: 10.1208/pt060480
Effects of Lyophilization on the Physical Characteristics and Chemical Stability of Amorphous Quinapril Hydrochloride
Author: Yushen Guo, Stephen R. Byrn, George Zografi

Keywords: amorphous,quinapril hydrochloride,lyophilization,chemical degradation,glass transition temperature,ACE inhibitor
Summary: Effects of Lyophilization on the lyophilization and to compare its physical characteristics and chemical Amorphous QHCl samples were prepared by lyophilization

Pharmaceutical Research; Vol. 17 Number 8, Aug 2000;Published Date:07/31/2000; DOI: 10.1023/A:1007519003070
Liposomal budesonide for dry powder inhaler: Preparation and stabilization
Author: Mayank R. Joshi, Ambikanandhan Misra

Keywords: Liposomes,dry powder inhaler,budesonide,lyophilization,drug retention
Summary: entrapped after lyophilization was optimized. lyophilization and rehydration. Lyophilization is

AAPS PharmSciTech; Vol. 2 Number 4, Dec 2001;Published Date:11/30/2001; DOI: 10.1007/BF02830565
Influence of Process Conditions on the Crystallization and Transition of Metastable Mannitol Forms in Protein Formulations During Lyophilization
Author: Wenjin Cao, Yong Xie, Sampathkumar Krishnan, Hong Lin, Margaret Ricci

Keywords: lyophilization,mannitol,metastable,Raman,Raman imaging
Summary: during lyophilization. A cryostage was used to mimic the different processing steps during lyophilization. forms in final lyophilization samples from the freeze-drying stage.

Pharmaceutical Research; Vol. 30 Number 1, Jan 2013;Published Date:12/31/2012; DOI: 10.1007/s11095-012-0855-9
Long-term Stability and in vitro Release of hPTH(1–34) from a Multi-reservoir Array
Author: Elizabeth R. Proos, James H. Prescott, Mark A. Staples

Keywords: drug delivery,microchip,osteoporosis,parathyroid hormone,protein and peptide formulation
Summary: purity after lyophilization, Sample Preparation for Bulk Lyophilization

Pharmaceutical Research; Vol. 25 Number 6, Jun 2008;Published Date:05/31/2008; DOI: 10.1007/s11095-008-9544-0
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