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Text: pH variations
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Investigating the Use of Liquisolid Compacts Technique to Minimize the Influence of pH Variations on Loratadine Release
Author: Mazen El-Hammadi, Nisrine Awad

Keywords: dissolution rate,liquisolid compacts,loratadine,pH variations,solubility
Summary: the Influence of pH Variations on Loratadine Release less affected by pH variation compared with conventionally made (direct compression) and commercial the effects of pH variation on the dissolution rate of drugs with poor water solubility.

AAPS PharmSciTech; Vol. 13 Number 1, Mar 2012;Published Date:02/29/2012; DOI: 10.1208/s12249-011-9719-6
PEG-Stabilized Micellar System with Positively Charged Polyester Core for Fast pH-Responsive Drug Release
Author: Hua-Fen Wang, Hui-Zhen Jia, Si-Xue Cheng, Jun Feng, Xian-Zheng Zhang, Ren-Xi Zhuo

Keywords: cationic polycarbonate,diblock terpolymer,mPEG-b-poly(ADMC-co-CL),pH-tunable drug release,polymeric micelles
Summary: PurposeTo design functional drug carriers for fast pH-responsive drug release. The pH-tunable morphology variation and drug release pattern were observed at different pH. in terms of the variation in CAC value and hydrodynamic size at different pH.

Pharmaceutical Research; Vol. 29 Number 6, Jun 2012;Published Date:05/31/2012; DOI: 10.1007/s11095-012-0669-9
Preparation and Evaluation of Gelatin/Sodium Carboxymethyl Cellulose Polyelectrolyte Complex Microparticles for Controlled Delivery of Isoniazid
Author: Nirmala Devi, Tarun Kumar Maji

Keywords: characterization,gelatin,isoniazid,microparticle,sodium carboxy methyl cellulose
Summary: temperature and pH release rate of isoniazid was more at higher pH compared to that of at lower pH.

AAPS PharmSciTech; Vol. 10 Number 4, Dec 2009;Published Date:11/30/2009; DOI: 10.1208/s12249-009-9344-9
Development of Enteric Coated Flurbiprofen Tablets using Opadry/acryl-eze System—A Technical Note
Author: Durriya Hashmat, M. Harris Shoaib, Zafar Alam Mehmood, Rabia Bushra, Rabia Ismail Yousuf, Fahim Lakhani

Keywords: acryl-Eze,direct compression,enteric coating,flurbiprofen,opadry
Summary: pH-sensitive enteric coating polymers today include: resistant to gastric juice but readily dissolve at a pH above Weight variation was

AAPS PharmSciTech; Vol. 9 Number 1, Mar 2008;Published Date:02/29/2008; DOI: 10.1208/s12249-007-9005-9
Enteric Coated Magnetic HPMC Capsules Evaluated in Human Gastrointestinal Tract by AC Biosusceptometry
Author: Luciana A. Corá, Fernando G. Romeiro, Fabiano C. Paixão, Madileine F. Américo, Ricardo B. Oliveira, Oswaldo Baffa, José Ricardo A. Miranda

Keywords: biosusceptometry,colonic drug delivery,gastrointestinal motility,HPMC capsules,magnetic images
Summary: pH-dependent solubility. between the luminal pH (5) recording the magnetic flux variation obtained from the

Pharmaceutical Research; Vol. 23 Number 8, Aug 2006;Published Date:07/31/2006; DOI: 10.1007/s11095-006-9035-0
In Vitro Assessment of NSAIDs-Membrane Interactions: Significance for Pharmacological Actions
Author: Cláudia Nunes, Daniela Lopes, Marina Pinheiro, Catarina Pereira-Leite, Salette Reis

Keywords: fluorescence,liposomes,NSAIDs,partition,thermodynamic parameters
Summary: two physiological pH conditions (pH 7.4 and 5.0) were investigated by time-resolved and steady-stat the membrane-water variation of enthalpy (H wm) and entropy (S wm) and consequently the Gibbs free at physiological pH of 7.4); and (ii) the protective membrane lining of the gastric mucosa (LUVs of

; DOI: 10.1007/s11095-013-1066-8
Formulation and Evaluation of Bi-layer Tablet of Metoclopramide Hydrochloride and Ibuprofen
Author: Bhavesh Shiyani, Surendra Gattani, Sanjay Surana

Keywords: bi-layer tablet,gellan gum,ibuprofen,metoclopramide hydrochloride
Summary: AAPS PharmSciTech, Vol. 9, No. 3, September 2008 ( # 2008) DOI: 10.1208/s12249-008-9116-y Research Article Formulation and Evaluation of Bi-layer Tablet of Metoclopramide Hydrochloride and Ibuprofen

AAPS PharmSciTech; Vol. 9 Number 3, Sep 2008;Published Date:08/31/2008; DOI: 10.1208/s12249-008-9116-y
Chitosan–Chondroitin Sulfate Based Matrix Tablets for Colon Specific Delivery of Indomethacin
Author: Jitendra R. Amrutkar, Surendra G. Gattani

Keywords: chitosan,chondroitin sulfate,colonic delivery,cross-linking,indomethacin
Summary: colonic delivery system based on time- and pH-dependent phosphate buffer at pH values higher than 6.5, and this system was very well established due to large variation in pH

AAPS PharmSciTech; Vol. 10 Number 2, Jun 2009;Published Date:05/31/2009; DOI: 10.1208/s12249-009-9253-y
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