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Author: Mazen El-Hammadi, Nisrine Awad
Keywords: dissolution rate,liquisolid compacts,loratadine,pH variations,solubility Summary: the Influence of pH Variations on Loratadine Release less affected by pH variation compared with conventionally made (direct compression) and commercial the effects of pH variation on the dissolution rate of drugs with poor water solubility.
AAPS PharmSciTech; Vol. 13 Number 1, Mar 2012;Published Date:02/29/2012; DOI: 10.1208/s12249-011-9719-6
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Author: Hua-Fen Wang, Hui-Zhen Jia, Si-Xue Cheng, Jun Feng, Xian-Zheng Zhang, Ren-Xi Zhuo
Keywords: cationic polycarbonate,diblock terpolymer,mPEG-b-poly(ADMC-co-CL),pH-tunable drug release,polymeric micelles Summary: PurposeTo design functional drug carriers for fast pH-responsive drug release. The pH-tunable morphology variation and drug release pattern were observed at different pH. in terms of the variation in CAC value and hydrodynamic size at different pH.
Pharmaceutical Research; Vol. 29 Number 6, Jun 2012;Published Date:05/31/2012; DOI: 10.1007/s11095-012-0669-9
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Author: Nirmala Devi, Tarun Kumar Maji
Keywords: characterization,gelatin,isoniazid,microparticle,sodium carboxy methyl cellulose Summary: temperature and pH
release rate of isoniazid was more at higher pH compared to that of at lower pH.
AAPS PharmSciTech; Vol. 10 Number 4, Dec 2009;Published Date:11/30/2009; DOI: 10.1208/s12249-009-9344-9
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Author: Durriya Hashmat, M. Harris Shoaib, Zafar Alam Mehmood, Rabia Bushra, Rabia Ismail Yousuf, Fahim Lakhani
Keywords: acryl-Eze,direct compression,enteric coating,flurbiprofen,opadry Summary: pH-sensitive enteric coating polymers today include: resistant to gastric juice but readily dissolve at a pH above
Weight variation was
AAPS PharmSciTech; Vol. 9 Number 1, Mar 2008;Published Date:02/29/2008; DOI: 10.1208/s12249-007-9005-9
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Author: Luciana A. Corá, Fernando G. Romeiro, Fabiano C. Paixão, Madileine F. Américo, Ricardo B. Oliveira, Oswaldo Baffa, José Ricardo A. Miranda
Keywords: biosusceptometry,colonic drug delivery,gastrointestinal motility,HPMC capsules,magnetic images Summary: pH-dependent solubility. between the luminal pH (5) recording the magnetic flux variation obtained from the
Pharmaceutical Research; Vol. 23 Number 8, Aug 2006;Published Date:07/31/2006; DOI: 10.1007/s11095-006-9035-0
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Author: Cláudia Nunes, Daniela Lopes, Marina Pinheiro, Catarina Pereira-Leite, Salette Reis
Keywords: fluorescence,liposomes,NSAIDs,partition,thermodynamic parameters Summary: two physiological pH conditions (pH 7.4 and 5.0) were investigated by time-resolved and steady-stat the membrane-water variation of enthalpy (H wm) and entropy (S wm) and consequently the Gibbs free at physiological pH of 7.4); and (ii) the protective membrane lining of the gastric mucosa (LUVs of
; DOI: 10.1007/s11095-013-1066-8
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Author: Bhavesh Shiyani, Surendra Gattani, Sanjay Surana
Keywords: bi-layer tablet,gellan gum,ibuprofen,metoclopramide hydrochloride Summary: AAPS PharmSciTech, Vol. 9, No. 3, September 2008 ( # 2008)
DOI: 10.1208/s12249-008-9116-y
Research Article
Formulation and Evaluation of Bi-layer Tablet of Metoclopramide
Hydrochloride and Ibuprofen
AAPS PharmSciTech; Vol. 9 Number 3, Sep 2008;Published Date:08/31/2008; DOI: 10.1208/s12249-008-9116-y
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Author: Jitendra R. Amrutkar, Surendra G. Gattani
Keywords: chitosan,chondroitin sulfate,colonic delivery,cross-linking,indomethacin Summary: colonic delivery system based on time- and pH-dependent
phosphate buffer at pH values higher than 6.5, and this
system was very well established due to large variation in pH
AAPS PharmSciTech; Vol. 10 Number 2, Jun 2009;Published Date:05/31/2009; DOI: 10.1208/s12249-009-9253-y
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