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Author: Ayyappa Chaturvedula, Dipty P. Joshi, Carter Anderson, Russ Morris, Walter L. Sembrowich, Ajay K. Banga
Keywords: granisetron,iontophoresis,microdialysis,pharmacokinetics
Summary: Animals received either subcutaneous or dermal microdialysis probes
identified in the subcutaneous and dermal profiles, indicating that subcutaneous structures are also The subcutaneous microdialysis
Pharmaceutical Research; Vol. 22 Number 8, Aug 2005;Published Date:07/31/2005; DOI: 10.1007/s11095-005-5335-z
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Author: Leonid Kagan, Michael R. Turner, Sathy V. Balu-Iyer, Donald E. Mager
Keywords: lymphatic absorption,pharmacokinetic modeling,saturable absorption,therapeutic proteins
Summary: volume on subcutaneous absorption of rituximab in rats and to explore absorption mechanisms using p intravenous and subcutaneous administration at the back, abdomen, and foot of rats. following subcutaneous injection was inversely related to the dose level.
Pharmaceutical Research; Vol. 29 Number 2, Feb 2012;Published Date:01/31/2012; DOI: 10.1007/s11095-011-0578-3
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Author: Feirong Kang, Jagdish Singh
Keywords: PLGA,microspheres,insulin,in vivo absorption,biocompatibility
Summary: AAPS PharmSciTech 2005; 6 (3) Article 61 (http://www.aapspharmscitech.org).
Preparation, In Vitro Release, In Vivo Absorption and Biocompatibility Studies
of Insulin-loaded Microspheres in Rabbits
Submitted:
AAPS PharmSciTech; Vol. 6 Number 3, Sep 2005;Published Date:08/31/2005; DOI: 10.1208/pt060361
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Author: Susan A. Charman, Danielle N. McLennan, Glenn A. Edwards, Christopher J. H. Porter
Keywords: insulin,subcutaneous,absorption,lymph,protein,bioavailability
Summary: eral lymphatics in insulin absorption following subcutaneous (SC) volume (9), subcutaneous blood flow (7,11), site of injection
the absorption of materials from the subcutaneous interstitial
Pharmaceutical Research; Vol. 18 Number 11, Nov 2001;Published Date:10/31/2001; DOI: 10.1023/A:1013046918190
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Author: Heidi J. Holovics, Carter R. Anderson, Barry S. Levine, Ho-Wah Hui, Craig E. Lunte
Keywords: iontophoresis,lidocaine,liquid chromatography,microdialysis,percutaneous,skin,sutured incision,transdermal drug delivery
Summary: Concentrations in localized areas (suture, dermis, subcutaneous, and vascular) dermis, suture, and subcutaneous regions by 6-, 15-, and 20-fold, respectively. suture concentration and in the subcutaneous region directly below the incision.
Pharmaceutical Research; Vol. 25 Number 8, Aug 2008;Published Date:07/31/2008; DOI: 10.1007/s11095-007-9490-2
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Author: Irmgard Tegeder, Jörn Lötsch, Martina Kinzig-Schippers, Fritz Sörgel, Gary R. Kelm, Stephen T. Meller, Gerd Geisslinger
Keywords: microdialysis,ketoprofen,NSAIDs,topical administration,population pharmacokinetic model
Summary: Muscle and subcutaneous tissue concentrations were as- tions of ketoprofen were achieved in subcutaneous and muscle tissue
cm) were inserted into the subcutaneous tissue and into the
Pharmaceutical Research; Vol. 18 Number 7, Jul 2001;Published Date:06/30/2001; DOI: 10.1023/A:1010940428479
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Author: Fang Wu, Suraj G. Bhansali, Wing Cheung Law, Earl J. Bergey, Paras N. Prasad, Marilyn E. Morris
Keywords: fluorescence imaging,lymphatic uptake,molecular weight,protein,subcutaneous injection
Summary: in Mice after Subcutaneous Injection: of loss from a subcutaneous (SC) injection site and subsequent uptake by the draining lymph nodes i subcutaneous injection
Pharmaceutical Research; Vol. 29 Number 7, Jul 2012;Published Date:06/30/2012; DOI: 10.1007/s11095-012-0708-6
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Author: Scott A. Burton, Chin-Yee Ng, Ryan Simmers, Craig Moeckly, David Brandwein, Tom Gilbert, Nathan Johnson, Ken Brown, Tesha Alston, Gayatri Prochnow, Kris Siebenaler, Kris Hansen
Keywords: transdermal drug delivery,microneedles,intradermal,hollow microstructures,MTS
Summary: challenges associated with subcutaneous injection by greatly
; DOI: 10.1007/s11095-010-0177-8
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